Indeed, diagnosed 2 months ago with ALL Philadelphia +. Treatment with lighter chemo and Glivec. Blasts decreased rapidly to 0.11% but then, some 3 weeks ago a high level (some 35% ) of Philadelphia+ was found. Immediately Glivec was changed for Sprycell and we do not know yet the results of that. Doctors ( he is treated in a University Hospital in Switzerland) presume now that this relapse is the result of the fact that he has been in a chronicle phase before the Acute phase and his decease is now CML in stead of ALL, but they can not confirm this for a 100% yet. Today we have been extensively informed about the SCT and all the risks and potential consequences, given also his age (74, although in very good shape). We tend towards waiting for the results of (heavier) chemo next week, together with the Sprycell, and take it from there.
Have you known similar cases before?
Thank you sincerely
Laura