dear madam,
my wife recently cml on 20-01-2016.
she was on imatinib 400mg daily.
on 20-04-2016 sampled PCR test report .
we cannot understand the report please explain.
bone marrow BIOPSY ; blast 1%
impression: hypocellular bone marrow
REPORT QUANTITATIVE RT-PCRfor Monitering M-BCR/ABL1 mRNA TRANSCRIPTS
bcr/abl copy number 1975
abl copy no 14765.5
international scale convertion factor 1.857
international scale normalised copy no 24.83%
kryotype: not possible due to unavalability of qualty metaphases
INTERNATIONALscale normalized copy number % 0.05 MMR
INTERNATIONALscale normalized copy number % 0.15 NO major molecluer respons
0.05 INTERNATIONALscale normalized copy number % 0.15 : GRAZY ZONE ARROUND MMR CUT OFF
IS-NCN is nagative- no fusion transcript were detected
detection limit of this assay : 0.001% bcr/abl1 (p210)NCN
and she was bone pain ;tramadol and acetoamenophen taking daily one tablet 37.5 and 325 mg is there any problem?