Hello All,
I am new to the group. Hope you can help answer my question.
History: I was diagnosed CML in 2001. After 2-3 years On gleevec 400mg, I was in major molecular response and then undetectable (0.000) for around > 10 years or so while on 400mg gleevec.
Now suddenly last month in my last Bcd-abl it showed that I am
0.018 and repeating it after a month, it's 0.021 so little bit higher than last one..
Is it considered gleevec resistance? Where I need to switch?
BTW:
I missed 3 doses or so in the last month and that is
Where it (Bcd-abl by PCR) came 0.018 but not sure if 3 days can be that critical. Also I don't take medicine at the same time sometimes with breakfast sometimes with late lunch. Can that suddenly change the response?
Any thoughts or similar situation insight is much appreciated..
Thanks
Raj