Hi all,
I am a CML patient from Hong Kong. Below is my CML profile. I am newly dx at Nov 2000. Then start hydrea to control the WBC. At 2003, start gleevec, the qpcr value is around 6%. At 2009, the qpcr raise to 21% and found a mutation M351T. Then I start Tasigna at 2010. At 2011, the qpcr drop to 0.02 and then came to zero and raise to 0.01. At 2013, qpcr keep zero until last report on Dec 2016 which show 0.0033.
My doc, told me that there is a fluctuation and I am at MR4. I said I have a little worry as I keep the pcru for about 3 years. My doc said it is good enough to keep under 0.1. So, just keep to monitor the qpcr value by every 6 months as usual.
Sorry for all, I have a worry because I have a mutation experience at before. After that, I have a stress about the qpcr number raise. Actually, I feel so stress for getting the qpcr result from the doc after mutation happened.
Does anyone has similar experience for qpcr fluctuation for sharing?
Thank you very much.
2000 newly dx
2003 start at Gleeve, qpcr 6%, never reach qpcr 3% at gleevec
2009 find mutation M351T and qpcr raise to 21%
2010 start Tasigna
2011 qpcr 0.02
2012 qpcr 0, qpcr 0.01
2013 qpcr negative until last report on Dec 2016
Dec 2016 0.0033