Sorry for the indelicate post here, but I'm really going out of my mind. I'm 8 months into my CML diagnosis, everything is going great with Tasigna EXCEPT for the last 3-4 months or so I have persistent, really bad itching on my testicles/pubic area and anus. Been using medicated moisturizing creams and they help dial down the itch for about 60-90 minutes but it always returns. Benadryl does nothing. My doctor insists it must just be some form of allergic reaction to the Tasigna (he said from the beginning that rash/itching was to be expected) and has prescribed Gabapentin but I'm hesitant to take it because its supposed to knock you out and I can't be drowsy for work. At this point though I'm about to give in and try it.
Anyhow, just wondering if anyone else on Tasigna or similar TKIs has had this problem and if so, what they ended up doing about it. I know for sure that Tasigna is giving me generalized skin issues - my skin is much drier than normal, and I'm getting spots on my face and scalp which is very unusual for me. But all of that I can deal with - its the constant "raw butt" and itchy testicles that are driving me mad. Its so bad I can't even exercise or walk long distances without my rear end flaring up like I've just wiped it with sandpaper.
HELP!