Hi all, haven't posted on here for a good while but just wanted to update that I will be 7 years on with CML and on drugs on 16th October! I had first 2 years on Imatinib 400mg, reached CCyR but I then plateaud which led to me being put onto Sprycel 100mg for the last 5 years. Have been at 0.003 (MMR 4-4.5) for last year and decided I wanted to explore stopping or a dose reduction. I have very little side affects apart from fatigue and some nerve issues in feet and fingers.
I chatted with the main guy at Kings and we decided to drop dose in half for a year to 50mg and monitor with a view to stopping in a years time. He said he wanted me to be at MMR4.5 for 2 years before stopping so believes this is the safest course of action. I started 50mg today and will keep you up to date with how it goes every 3 months. Fingers crossed and hopefully my immune system will have learnt how to deal with the CML...