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Platelets

With decrease of dose of sprecel from 100 mg to 50mg my plateles increase in a one week from 15 to 50. And doctor advise me take one 50mg and next day 100mg fo two weeks and repeat cbc . Any one experence for that.

Obviously, your doctor is, rightly, being cautious because you have only just started therapy. I think alternating the dose between 50mg one day and 100mg the next day is a rational approach until your platelets stabilise and your response to your therapy can be assessed over the next few months. I do know many respond well to 50mg dasatinib.

Sandy

Sandy thanks your adivice give me lot of suport when my platelets was very low.

my mother had a similar situation with gleevec , her values was better( no neutropenia or no trompocitopenia ) but speed of dropping was so fast doctor decreased her daily dosage from 400 mg to 300 mg.

here is a link for sprycel tabs . look for 2.3 dose adjustment for adverse reactions .. 

i wasnt aware of this sources so we go with doctors way. i think both ways work.

 

http://packageinserts.bms.com/pi/pi_sprycel.pdf