I am just seeking a bit of info regarding a spike in cramps. For approximately 3 weeks now I have had acute spasms/cramps in the soles of my feet, neck and back, making tasks even more troublesome than before.
My BCR/ABL is in decent order, I have historically low vitamin D results, an elevated IGA and today I was told by medic I would be classed as anemic if I was a women (I am not) but apparently that's fine?
Just wondered if anyone had any thoughts? I eat a balanced diet, had CML for 4 years and been on Bosutinib for 2 years. I have have been plagued by musculoskeletal pain/stiffness since around the time of my Diagnosis/Treatment, and have been through 4 TKIs. One of the biggest issues is stretching can help cramps but I struggle to stretch due to mobility issues and pain intensifying or prolonged carry over. I am 37, previously no issues.
I am also combining pain relief from codeine to anti inflammatorys too.
I asked the consultant today if there was a test that measures the toxicity of the TKI and how my body metobolises them, for instance a particular assay/test but was told no. Has anyone had a test like this, or know of one routinely (UK based)? Would anyone recommend such a thing if one does exist, my thoughts would be how much TKI am I absorbing due to how my PCR plummets on treatment but rockets up during short breaks.
Any advice appreciated.