ive been diagnosed with CML back in Sept 2017. Was first put on hydroxyurea then started on Nilotinib. However after a week into Nilotinib, my liver function test went up very high that my doctor ordered me to stop Nilotinib. A week later I was asked to turn on Imatinib 400mg. As I am also having some problems with my uric levels, I also had to take Allopurinol. 1.5 months into Imatinib, my WBC became very low (2.2). So my doc asked me to Change to 300mg per day. She told me that anything below 300mg, the body would start to build resistance.
my question: what does extreme low WBC means?how will it impact my PCR results? My doc said I’m a special case which develops high sensitivity to TKIs...