So my wife sends me this link and I am wondering if anyone here has any thoughts on whether or not this would be a good tool to use to determine which TKI might have the fewest and/or least severe side effects for a particular person willing to do this test.
https://sciencebasedmedicine.org/genomic-testing-at-your-pharmacy-ready-...
I realize there are other reasons to choose one TKI versus another, but could this be another viable tool to help make the decision if there is no other clear cut reason to choose one TKI over another. I know in my case, I was a suitable candidate for imatinib, dasatinib or nilotinib. My oncologist recommended nilotinib because he said it was more powerful than imatinib and less "dirty" (fewer off-target effects) than dasatinib. For over 2 years now, I have wondered if this was the right choice or if it really didn't matter. My response to nilotinib has been excellent, but boy did I have a lot of off-target effects during the first 6 - 9 months. Fortunately for me, dose reduction (now on 150 mg/day versus starting dose of 600 mg/day) resolved most of these, so I have stayed on nilotinib.
