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Anyone ever have multiple tests with unobtainable results (MD Anderson) Trey or Scuba (if you're still on the boards)

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I had blood work on April 10th and the report came back "RNA is inadequate for BCR/ABL1 testing by PCR as judged by sub-optimal amplification of internal control". My doctor reordered the test and I had blood drawn again on April 27th. Just received a phone call that the same problem occurred. Anyone have any idea what would cause this? My previous results were <.01%, which is essentially undetectable at MD Anderson.

Hi - you might find some of the content in section 3 & 4 (page 14+) from our PCR Booklet helpful in understanding why PCR tests can sometimes fail or be inaccurate.

You can find it here - just click on the icon.

https://www.cmlsupport.org.uk/section/pcr-booklet

 

David.